Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1979-07-11
1982-10-05
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
26032615, 424251, 424258, 424270, 424272, 424273R, 424273B, 424274, 544284, 544237, 544253, 544283, 544333, 544334, 544335, 544336, 544353, 544354, 544356, 544405, 544408, 544409, 546118, 546141, 546145, 546153, 546165, 548179, 548217, 548327, 548333, 548336, 548341, A61K 31495, C07D24112
Patent
active
043528040
ABSTRACT:
Oxime ether derivatives of the formula (I): ##STR1## wherein Het is a monocyclic heteroaromatic group containing two hetero atoms at least one of which is nitrogen, or a bicyclic heteroaromatic group containing one or two hetero atoms at least one of which is nitrogen, Ar is a phenyl or a 5- or 6-membered monocyclic heteroaromatic group, and R is an alkyl, alkenyl, alkynyl, cyanoalkyl, carbamidoalkyl or aminoalkyl group, or N-oxides thereof, have anti-ulcer activity in the gastro-intestinal tract of mammals.
REFERENCES:
patent: 3205234 (1965-09-01), Schumann
patent: 3957805 (1976-05-01), Fanshawe et al.
Niemers, et al., "Synthesis", 1976, pp. 593-595.
Villani, et al., "J. Pharm. Sci.", vol. 58, 1969, p. 139.
ACF Chemiefarma NV
Daus Donald G.
Turnipseed James H.
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