Oxidoreductase and method for preparing 3-(p-hydroxyphenyl)-2-pr

Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving oxidoreductase

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435189, 435147, C12Q 126, C12N 902, C12P 724

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active

060177241

ABSTRACT:
The present invention relates to a novel enzyme which is derived from bacterial cells of a strain belonging to the genus Pseudomonas fluorescens and which catalyzes a reaction for oxidizing substrates such as p-hydroxytoluene derivatives and p-alkylphenol derivatives as well as a method for preparing, for instance, 3-(p-hydroxyphenyl)-2-propenol derivatives, p-hydroxybenzaldehyde derivatives, p-alkylphenol derivatives and optically active S(-)-1-(4-hydroxyphenyl) alcohol derivatives, using the enzyme.

REFERENCES:
Fraaije et al., "Substrate specificity of flavin-dependent vanillyl-alcohol oxidase from Penicillium simplicissimum, Evidence for the production of 4-hydroxycinnamyl alcohols from 4-allyphenols", Eur. J. Biochem. 234, 271-277 (1995).
Tadasa, "Degradation of Eugenol by a Microorganism", Agric. Biol. Chem., 41 (6), 925-929, 1977.
Tadasa et al., "Initial Steps of Eugenol Degradation Pathway of a Microorganism", Agric. Biol. Chem. 47 (11), 2639-2640, 1983.

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