Oxidized-type glutathione alkyl ester

Details Oxidized-type glutathione alkyl ester Oxidized-type glutathione alkyl ester

1991-12-27

1993-06-29

Cashion, Jr., Merrell C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

530331, 530332, 530345, A61K 3700, A61K 3702

Patent

active

052234886

ABSTRACT:
Presented are an oxidized-type glutathione alkyl ester represented by the formula (I). ##STR1## wherein R denotes a lower alkyl group, and a salt thereof: a method of preparing said ester which is comprised of oxidizing a reduced-type glutathione monoalkyl ester represented by the formula (II), ##STR2## wherein R is as defined above, with the air, hydrogen peroxide or iodine in an aqueous solution: and a pharmaceutical composition and method for suppression of hepatic disorders characterized in that it contains as an active constituent said ester or a pharmaceutically acceptable salt thereof.

REFERENCES:
CA 110: 121380x (1989).
JP Abstract vol. 13 No. 208 (May 16, 1989) of JP 64-26516 (Akira Otsu et al.).
Japanese Unexamined Patent Publication No. 15870/1986 (61-15870).

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