Organic compounds -- part of the class 532-570 series – Organic compounds – Phosphorus esters
Reexamination Certificate
2011-03-15
2011-03-15
Shiao, Rei-tsang (Department: 1628)
Organic compounds -- part of the class 532-570 series
Organic compounds
Phosphorus esters
C548S405000, C548S413000, C435S004000
Reexamination Certificate
active
07906674
ABSTRACT:
The invention relates to oxidized phospholipids having one of the general formulas (I) or (II) wherein A═O, C, NH, or S; B═O, C, NH, or S; and R2is selected from the group consisting of —CO—(CH2)n—CH3; —CO—(CH2)n—CHO; and —CO—(CH2)n—COOH, with n=3-7, with the proviso that in general formula (I), R1is selected from the group consisting of —CH2—(CH2)n—X; and —CO—(CH2)n—X with n=5-11, wherein X is a fluorophore; and in general formula (II), R1is selected from the group consisting of —CH═CH—(CH2)n—CH3with n=9-15; —(CH2)n—CH3with n=11-17; and —CO—(CH2)n—CH3with n=10—16; and R3is selected from the group consisting of —CO—(CH2)n—X; and —SO2—(CH2)n—X, with n=0-5, wherein X is a fluorophore.
REFERENCES:
patent: 4668623 (1987-05-01), Kinnunen et al.
patent: 1 318 154 (2003-06-01), None
patent: 2002-223794 (2002-08-01), None
patent: 00/32808 (2000-06-01), None
patent: 01/75170 (2001-10-01), None
www.abcam.com/technical., 2010.
Puliikunnil et al.,2004, CAS: 141:363846.
Kofune et al., 2000, CAS: 133:355202.
Trenker, M. et al., “Fluorescence Microscopy Reveals Rapid Import of Oxidized Phospholipids into Vascular Smooth Muscle Cells,” Joint Annual Meeting 2003: OGBM, ÖGGGT, ÖGBT, ANGT, Graz, Austria, Sep. 21, 2003, 4P-0973.
Kofune H et al: “Molecular recognition of vesicles containing pyrene compounds using fluorescence spectroscopy,” Polymer Preprints, vol. 41, No. 2, Aug. 2000, pp. 1701-1702, XPOO1248221.
Kilpatrick P K et al: “Selective precipitation of antibody with ligand-modified phospholipids: Effect of lipid chain length,” Biotechnology Progress, vol. 13, No. 4, Jul. 1997, pp. 446-452, XP002408845.
Kinsky S C et al: “Circumvention of the methotrexate transport system by methotrexate-phosphatidylethanolamine derivatives: Effect of fatty acid chain length,” Biochimica et Biophysica ACTA, vol. 921, No. 1, 1987, pp. 96-103, XP002408846.
Vaz W L et al: “Translational diffusion of lipids in liquid crystalline phase phosphatidylcholine multibilayers. A comparison of experiment with theory.” Biochemistry, vol. 24, No. 3, Jan. 29, 1985, pp. 781-786, XP002408847.
Vaz W L C et al: “Experimental evidence against the applicability of the Saffman-Delbrück model to the translational diffusion of lipids in phosphatidylcholine bilayer membranes,” FEBS Letters, vol. 152, No. 2, Feb. 1983, pp. 287-290, XP009075372.
Hermetter Albin
Trenker Michael
Bradley Arant Boult & Cummings LLP
Shiao Rei-tsang
LandOfFree
Oxidized phospholipids does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Oxidized phospholipids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oxidized phospholipids will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2623422