Coating processes – Medical or dental purpose product; parts; subcombinations;... – Analysis – diagnosis – measuring – or testing product
Patent
1997-12-04
1999-04-06
Dudash, Diana
Coating processes
Medical or dental purpose product; parts; subcombinations;...
Analysis, diagnosis, measuring, or testing product
4241301, 424 943, 427 212, 427 224, 427 225, 427 23, 427 231, 427338, 435174, 435176, 435181, 435188, 523112, 523113, B05D 310, A61L 2700, A61L 3300
Patent
active
058915060
ABSTRACT:
A method for making a medical device having at least one glycoprotein and/or glycopeptide immobilized on a substrate surface is provided. The method may include oxidizing 1,2 dihydroxy moieties with a periodate to form an aldehyde-functional material; combining the aldehyde-functional material with an amino-functional material to bond the two materials together through an imine moiety; and reacting the imine moiety with a reducing agent to form a secondary amine. Another method of the present invention may be employed to crosslink glycoproteins and/or glycopeptides immobilized on medical device surfaces. Additionally, one method of the present invention may be employed to crosslink glycoproteins and/or glycopeptides, thereby forming a crosslinked biomaterial or a crosslinked medical device coating.
REFERENCES:
patent: 3826678 (1974-07-01), Hoffman et al.
patent: 4521564 (1985-06-01), Solomon et al.
patent: 4600652 (1986-07-01), Solomon et al.
patent: 4613665 (1986-09-01), Larm
patent: 4642242 (1987-02-01), Solomon et al.
patent: 4720512 (1988-01-01), Hu et al.
patent: 4786556 (1988-11-01), Hu et al.
patent: 5032666 (1991-07-01), Hu et al.
patent: 5053048 (1991-10-01), Pinchuk
patent: 5057313 (1991-10-01), Shih
patent: 5077372 (1991-12-01), Hu et al.
patent: 5104976 (1992-04-01), Casellas et al.
patent: 5258501 (1993-11-01), Barbaric et al.
patent: 5274119 (1993-12-01), Frazier et al.
patent: 5344455 (1994-09-01), Keogh et al.
patent: 5362852 (1994-11-01), Geoghegan
patent: 5443953 (1995-08-01), Hansen et al.
patent: 5521290 (1996-05-01), Sivam et al.
patent: 5532352 (1996-07-01), Pliura et al.
patent: 5614487 (1997-03-01), Battersby et al.
patent: 5672638 (1997-09-01), Verhoeven et al.
patent: 5677276 (1997-10-01), Dickerson et al.
patent: 5728420 (1998-03-01), Keogh
patent: 5795560 (1998-08-01), Reed
R. G. Dickinson, et al., "A New Sensitive and Specific Test for the Detection of Aldehydes: Formation of 1719-1720 (1970) ( no month).
K.F. Geoghegan, et al., "Site-Directed Conjugation of Nonpeptide Groups to Peptides and Proteins via Periodate Oxidation of a 2-Amino Alcohol. Application to Modification at N-Terminal Serine," Bioconjugate Chem., 3, 138-146 (1992) (no month).
A.S. Hoffman, et al., "Covalent Binding of Biomolecules to Radiation-Grafted Hydrogels on Inert Polymer Surfaces," Trans. Am. Soc. Artif. Intern. Organs, 18, 10-18 (1972) (no month).
S. Holmes, et al. "Covalent Binding of Biomolecules to Radiation-Grafted Hydrogels on Inert Polymer Surfaces," Trans. Am. Soc. Artif. Intern. Organs, 18, 0-18 (1972) (no month).
Y. Ito, et al., "Materials for Enhancing cell Adhesion by Immobilization of Cell-Adhesive Peptide," Biomed. Mat. Res., 25, 1325-1337 (1991) (No month).
P.H. O'Farrell, "High Resolution Two-Dimensional Electrophoresis of Proteins," J. Biol. Chem., 250, 4007-4021 (1975) May.
Dudash Diana
Medtronic Inc.
Patton Harold R.
Woods Thomas F.
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