Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-04-26
1994-08-09
Ivy, C. Warren
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544172, 549510, 549511, A61K 31335, C07D30514
Patent
active
053366840
ABSTRACT:
Antineoplastic taxol derivatives are derived by selective oxidation of the alkene portion of the side chain of cephalomannine. The derivative displays high activity in promoting assembly of microtubulin and also displays cytotoxic activity against malignant cells.
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Beckvermit Jeffrey T.
Murray Christopher K.
Ziebarth Timothy D.
Edmundson Dean P.
Hauser Chemical Research, Inc.
Ivy C. Warren
Trinh Ba K.
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