Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1987-12-17
1990-06-05
Hollrah, Glennon H.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514317, 514449, 548517, 546207, 549263, A61K 31365, C07D40512
Patent
active
049314637
ABSTRACT:
Racemic compounds of the formula ##STR1## wherein R.sup.1, R.sup.2, R.sup.3, R.sup.4, R.sup.5 and n are as described herein, enantiomers and diastereomers thereof, and salts of these esters with weak acids, are described. These compounds inhibit pancreas lipase and are useful agents in the treatment of obesity, hyperlipaemia, atherosclerosis and arteriosclerosis.
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Barbier Pierre
Schneider Fernand
Widmer Ulrich
Gould George M.
Hoffmann-La Roche Inc.
Hollrah Glennon H.
Isgro William G.
Leon Bernard S.
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