Oxazolyl-aryloxyacetic acid derivatives and their use as...

Details Oxazolyl-aryloxyacetic acid derivatives and their use as... Oxazolyl-aryloxyacetic acid derivatives and their use as...

2007-02-13

2007-02-13

Saeed, Kamal A. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S236000

Reexamination Certificate

active

10343187

ABSTRACT:
Novel compounds that are modulators of PPAR receptors, and pharmaceutically acceptable salts, solvates and hydrates thereof, processes for making the compounds, pharmaceutical compositions containing the compounds, or pharmaceutically acceptable salts, solvates and hydrates thereof

REFERENCES:
patent: 5089514 (1992-02-01), Hulin
patent: 5232945 (1993-08-01), Hulin
patent: 5306726 (1994-04-01), Hulin
patent: 5902726 (1999-05-01), Kliewer et al.
patent: 5994554 (1999-11-01), Kliewer et al.
patent: 0 930 299 (1999-07-01), None
patent: 2 359 082 (2001-08-01), None
patent: WO 97 28115 (1997-08-01), None
patent: WO 97 31907 (1997-09-01), None
patent: WO 99 46232 (1999-09-01), None
patent: WO 01 16120 (2001-03-01), None
patent: WO 02 16331 (2002-02-01), None
patent: WO 02 18355 (2002-03-01), None
Sarges, R., et al. : “Glucose Transport—Enhancing and Hypoglycemic Activity of 2-Methyl-2-Phenoxy-3-Phenylpropanoic Acids”; Journal of Medicinal Chemistry, vol. 39, No. 24, Nov. 22, 1996, pp. 4783-4803.
Cobb, J. E., et al. : “N-(2-Benzoylphenyl) -L-Tyrosine PPARGamma Agonists. 3.Structure-Activity Relationship and Optimization of the N-Aryl Substituent”; Journal of Medicinal Chemistry, vol. 41, No. 25, Dec. 3, 1998, pp. 5055-5069.
Bright, S.W., et al. : “Competitive Particle Concentration Fluorescence Immunoassays for Measuring Anti-Diabetic Drug Levels in Mouse Plasma”; Journal of Immunological Methods, vol. 207, No. 1, Aug. 22, 1997 (Aug. 2, 1997), pp. 23-31.
Brooks, D., et al. : “Design and Synthesis of 2-methyl-2-{4-′2-′5-methyl-2-aryloxazol-4-yl)ethoxylphenoxy}propionic acids: A New Class of Dual PPARAlpha/Gamma Agonists”; Journal of Medicinal Chemistry, vol. 44, No. 13, Jun. 21, 2001, pp. 2061-2064.
Shinkai, H. et al. : “Isoxazolidine-3, 5-dione and Noncyclic 1, 3-dicarbonyl Compounds as Hypoglycemic Agents”; Journal of Medicinal Chemistry, vol. 41, No. 11, May 21, 1998, pp. 1927-1933.
Murugesan, N., et al. : “Biphenylsulfonamide Endothelin Receptor Antogonists 2. Discovery of 4′-oxazoly-lbiphenylsulfonamides as a New Class of Poent, Highly Selective ET(A)Antagonists”; Journal of Medicinal Chemistry, vol. 43, No. 16, Aug. 10, 2000, pp. 3111-3117.
Malamas, M.S., et al. : “Azole Phenoxy Hydroxyureas as Selective and Orally Active Inhibitors fo 5-Lipoxygenase”; Journal of Medicinal Chemistry, vol. 39, No. 1, Jan. 5, 1996, pp. 237-245.
Merguro, K., et al. : “Studies on Antidiabetic Agents. VII. Synthesis and Hypoglycemic Activity fo 4-Oxazoleacetic Acid Derivatives”; Chemical & Pharmaceutical Bulletin, vol. 34, No. 7, 1986, pp. 2840-2851.

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