Oxazolidinone photoaffinity probes

Details Oxazolidinone photoaffinity probes Oxazolidinone photoaffinity probes

2005-02-22

2005-02-22

Saeed, Kamal (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C514S378000, C548S228000, C548S247000

Reexamination Certificate

active

06858635

ABSTRACT:
Disclosed are novel compounds that are useful and effective as photoaffinity probes and methods of using oxazolidinone photoaffinity probes.

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Matassova, et al., “Ribosomal RNA is the target for oxazolidinones, a novel class of translation inhibitors,” RNA (1999) 5:939-946.
Porse et al, “Direct crosslinking of the antitumorantibiotic sparsomycin, and its derivatives, to A2602 in peptidyl transferase center of 23S-like rRNA within ribosome tRNA complexes,” Proc. Natl. Acad. Sci. USA (1999) 96:9003-9008.

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