Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1993-12-06
1994-10-18
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546275, 548230, C07D26324, A61K 3142
Patent
active
053569180
ABSTRACT:
Compounds of formula (I): ##STR1## wherein W represents an oxygen atom and X represents a group of formula --N(R.sup.1)--; R.sup.1 is hydrogen, alkyl or aralkyl; R.sub.2 and R.sup.3 are each hydrogen, alkyl, aralkyl, aryl or aromatic heterocyclic; R.sup.4 is hydrogen, alkyl or aralkyl; and A is alkylene which is optionally substituted by carboxy; and pharmaceutically acceptable salts and esters thereof, have a valuable vasodilatory activity.
REFERENCES:
patent: 4200640 (1980-04-01), Nagano et al.
patent: 4923886 (1990-05-01), Shiokawa et al.
patent: 5010093 (1991-04-01), Shiokawa et al.
Ishihara Sadao
Koike Hiroyuki
Miyake Shigeki
Mizuno Hiroshi
Saito Fujio
Gerstl Robert
Sankyo Company Ltd.
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