Oxazolidin-2-one and thiazolidin-2-one derivatives for use...

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

Reexamination Certificate

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Details

C514S382000, C514S376000, C548S186000, C548S189000, C548S253000, C548S254000, C548S231000

Reexamination Certificate

active

07109223

ABSTRACT:
This invention relates to potent selective agonists of the EP4subtype of prostaglandin E2 receptors, their use or a formulation thereof in the treatment of glaucoma and other conditions which are related to elevated intraocular pressure in the eye of a patient. This invention further relates to the use of the compounds of this invention for mediating the bone modeling and remodeling processes of the osteoblasts and osteoclasts.

REFERENCES:
Kubodera, et al. Heterocycles (1982), 18, p. 259-63 (STN search report and abstract).

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