Oxazole, isoxazole, thiazole and isothiazole amides

Details Oxazole, isoxazole, thiazole and isothiazole amides Oxazole, isoxazole, thiazole and isothiazole amides

1976-02-18

1977-01-04

Coughlan, Jr., Paul M.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602564Q, 424251, C07D23984

Patent

active

040012379

ABSTRACT:
Compounds having the formula ##STR1## wherein Z is a substituted or unsubstituted oxazole, is isoxazole, thiazole or isothiazole group are potent antihypertensive drugs which have generally less .alpha.-adrenergic blocking activity than does 2-[4-(2-furoyl)-piperazin-1-yl]-4-amino-6,7-dimethoxy-quinazoline which is a known potent antihypertensive drug.

REFERENCES:
patent: 3511836 (1970-05-01), Hess
patent: 3935213 (1976-01-01), Hess

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