Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Reexamination Certificate
2007-09-25
2007-09-25
Owens, Amelia A. (Department: 1625)
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C546S268400, C546S164000, C546S271400, C544S284000, C544S353000
Reexamination Certificate
active
10667187
ABSTRACT:
Novel oxazole and thiazole compounds, including derivatives thereof, to intermediates for their preparation, to pharmaceutical compositions containing them and to their medicinal use are described. The compounds of the present invention are potent inhibitors of transforming growth factor (“TGF”)-β signaling pathway. They are useful in the treatment of various TGF-related disease states including, for example, cancer and fibrotic diseases.
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Blumberg Laura C.
Munchhof Michael J.
Benson Gregg C.
Munchhof Martha G.
Owens Amelia A.
Pfizer Inc.
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