Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-01-02
2007-01-02
Stockton, Laura L. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S374000, C548S200000, C548S236000
Reexamination Certificate
active
10478936
ABSTRACT:
A compound of formula (I) and pharmaceutically acceptable salts, solvates and hydrolysable esters thereofWhereinX1represents O or S;R1and R2are independently H or C1-3alkyl or R1and R2which are bonded to the same carbon atom may together with the carbon atom to which they are bonded form a 3–5 membered cycloalkyl ring;R3and R4independently represent H, halogen, —CH3and —OCH3;R5represents H or C1-6alkylX2represents NH, NCH3or O;One of Y and Z is N, and the other is O or S;R6represents phenyl or pyridyl (wherein the N is in position 2 or 3) and is optionally substituted by one or more halogen, CF3, C1-6straight or branched alkyl (optionally substituted by halogen), with the provision that when R6is pyridyl, the N is unsubstituted.
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Forman, B.M., et al. Hypolipidemic Drugs, Polyunsaturated Fatty Acids, And Eicosanoids Are Ligands For Peroxisome Proliferator-Activated Receptors Alpha and Delta. Proceedings of the National Academy of Sciences of USA, National Academy of Science. Washington, US, vol. 94, Apr. 1997, pp. 4312-4317.
Fox Jennifer L.
Glaxo Group Limited
Stockton Laura L.
LandOfFree
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