Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1975-07-07
1977-03-15
Meyers, Albert T.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
260244R, 260246B, 42424855, 42424857, 42424858, A01N 900, A01N 922, C07D26500, C07D27300
Patent
active
040125114
ABSTRACT:
Oxazinoindole derivatives characterized by having an amino(lower)alkyl radical attached to the 1 position of a 1H-1,4-oxazino[4,3-a]indole nucleus are disclosed. The amino portion of the amino(lower)alkyl radical may be further substituted with one or two lower alkyl groups or incorporated in a heterocyclic amine radical. The derivatives are substituted further at positions 1 and 10 and may be optionally substituted at positions 3, 4, 6, 7, 8 and 9. The oxazinoindole derivatives of this invention are useful antidepressant and antiulcer agents. Methods for the use of these derivatives and compositions containing them are also disclosed.
REFERENCES:
patent: 3532719 (1970-10-01), Theimer
patent: 3676439 (1972-07-01), Hoffer
patent: 3833575 (1974-09-01), Demerson et al.
patent: 3852284 (1974-12-01), Fauran
Rieche et al., "Synthetic Methods of Org. Chem.," vol. 12, p. 361, S. Karger (pub.), N.Y. (1958).
Warren et al., "Synthetic Methods of Org. Chem.," vol. 13, pp. 361-362, S. Karger (pub.), N.Y. (1959).
Demerson Christopher A.
Dobson Thomas A.
Humber Leslie G.
Jirkovsky Ivo
Santroch George
Ayerst McKenna & Harrison Ltd.
Meyers Albert T.
Robinson D. W.
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