Oxazinoindole- and thiazinoindole derivatives

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260243R, 260246, C07D26516, C07D27300, C07D29500

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active

039622363

ABSTRACT:
Oxazinoindole derivatives characterized by having an amino(lower)alkyl radical attached to the 1 position of a 1H-1,4-oxazino[4,3-a]indole nucleus are disclosed. The amino portion of the amino(lower)alkyl radical may be further substituted with one or two lower alkyl groups or incorporated in a heterocyclic amine radical. The derivatives are substituted further at positions 1 and 10 and may be optionally substituted at positions 3, 4, 6, 7, 8 and 9. The oxazinoindole derivatives of this invention are useful antidepressant and antiulcer agents. Methods for the preparation and use of these derivatives are also disclosed.

REFERENCES:
patent: 3532719 (1970-10-01), Theimer
patent: 3676439 (1972-07-01), Hoffer
patent: 3833575 (1974-09-01), Demerson et al.
Rieche et al., "Synthetic Methods of Org. Chem." vol. 12, p. 361, S. Karger (pub.), New York (1958).
Warren et al., "Synthetic Methods of Org. Chem.", vol. 13, pp. 361-362, S. Karger (pub.), New York (1959).

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