Oxamic acid derivatives for the prevention of immediate type hyp

Details Oxamic acid derivatives for the prevention of immediate type hyp Oxamic acid derivatives for the prevention of immediate type hyp

1976-03-23

1978-01-17

Schenkman, Leonard

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Recombinant or stably-transformed bacterium encoding one or...

260518A, 260518R, 260519, 424300, 424309, 560193, 560 19, 560 45, 560 42, 560 47, 560 22, 560 43, 560 12, 560 44, 560 9, 560 13, A61K 31195

Patent

active

040693430

ABSTRACT:
Anti-allergic agents of aromatic oxamic acid derivation present the following formula: ##STR1## in which A is a member selected from the group consisting of .alpha.-naphthyl, .beta.-naphthyl, phenyl, 2,6-dichlorophenyl, and substituted phenyl moieties containing from one to three substituents in any of the 2,3,4 and 5 positions of the phenyl ring, independently selected from the group consisting of lower alkyl, lower alkylthio, lower alkylsulfinyl, lower alkoxy, hydroxy (lower)alkoxy, 2-(oxalyloxy) ethoxy, benzyloxy, N-mono- and di-lower alkylamino(lower)alkoxy, halo, sulfamyl, polyhalo(lower)alkyl, carbamyl, N-lower alkylcarbamyl, nitro, mono and di lower alkylamino, carboxy, lower alkylcarbonyl, carb(lower)alkoxy, phenoxy(lower)alkoxy, and oxalamidophenoxy radicals;
And pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 3317584 (1967-05-01), Stoffel
patent: 3511804 (1970-05-01), Duennenberger et al.
patent: 3987192 (1976-10-01), Wright
Petyunia et al., J. General Chem., USSR, vol. 34, No. 1, pp. 28-32, Jan. 1964.

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