Oxamic acid derivatives

Details Oxamic acid derivatives Oxamic acid derivatives

1977-09-19

1979-05-15

Thomas, Jr., James O.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

562437, 562453, 562455, 562456, C07C10142

Patent

active

041549619

ABSTRACT:
Anti-allergic agents of aromatic oxamic acid derivation present the following formula: ##STR1## in which A is a member selected from the group consisting of .alpha.-naphthyl, .beta.-naphthyl, phenyl, 2,6-di-chlorophenyl, and substituted phenyl moieties containing from one to three substituents in any of the 2,3,4 and 5 positions of the phenyl ring, independently selected from the group consisting of lower alkyl, lower alkylthio, lower alkylsulfinyl, lower alkoxy, hydroxy (lower)alkoxy, 2-(oxalyloxy) ethoxy, benzyloxy, N-mono- and di-lower alkylamino(lower)alkoxy, halo, sulfamyl, polyhalo(lower)alkyl, carbamyl, N-lower alkylcarbamyl, nitro, mono and di lower alkylamino, carboxy, lower alkylcarbonyl, carb(lower)alkoxy, phenoxy(lower)alkoxy, and oxalamidophenoxy radicals;
And pharmaceutically acceptable salts thereof.

REFERENCES:
patent: 2274716 (1942-03-01), Lyford
patent: 3683020 (1972-08-01), Luethi et al.
patent: 3906033 (1975-09-01), Biland et al.
patent: 3993079 (1976-11-01), Hall et al.
patent: 4017538 (1976-04-01), Hall et al.

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