Oxadiazole derivatives for inhibition of gamma secretase

Details Oxadiazole derivatives for inhibition of gamma secretase Oxadiazole derivatives for inhibition of gamma secretase

2007-01-02

2007-01-02

Lambkin, Deborah C. (Department: 1626)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C548S134000

Reexamination Certificate

active

10511915

ABSTRACT:
Compounds of formula I: wherein X represents a 5-(R-substituted)-1,2,4-oxadiazole-3-yl moiety are inhibitors of gamma-secretase, and hence useful for treating Alzheimer's disease

REFERENCES:
patent: 7041688 (2006-05-01), Campbell et al.
patent: 7041689 (2006-05-01), Collins et al.
patent: 7078424 (2006-07-01), Hamilton et al.
patent: WO 01/70677 (2001-09-01), None
patent: WO 02/36555 (2002-05-01), None

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