Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-03-13
2007-03-13
McKane, Joseph K. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S215000
Reexamination Certificate
active
10482231
ABSTRACT:
The present invention provides medicinal compositions characterized by comprising as the active ingredient either a compound represented by a formula [I] or a pharmaceutically acceptable composite thereof;[wherein X represents oxygen or sulfur; R1represents e.g., C1-4alkyl, phenyl optionally substituted, etc.; Q1represents spacer consisted of 0 to 3 carbon atoms; R2represents, e.g., phenyl optionally substituted; R3represents, e.g., hydrogen, C1-4alkyl, or a group represented by the following formulae; —CONH—R6; R4and R5represent e.g., nitro, cyano, C1-4alkylcarbonyl, respectively];in particular, medicine which is useful as therapeutic and/or protective drugs for inflammatory diseases and/or allergic diseases by improving sick conditions accompanied with the stimulated phospholipase A(2) activity.
REFERENCES:
patent: 4290870 (1981-09-01), Kondoh et al.
patent: 5198454 (1993-03-01), Chiou
patent: 5955616 (1999-09-01), Ohtani et al.
patent: 6762200 (2004-07-01), Takagi et al.
patent: 2004/0220244 (2004-11-01), Takagi et al.
patent: 0 081 584 (1983-06-01), None
patent: 2023857 (1980-01-01), None
patent: 53-152091 (1979-11-01), None
patent: WO 00/42031 (2000-07-01), None
patent: WO 01/72723 (2001-10-01), None
Hosomi et al., J. of Organic Chemistry, 1990, 55(19):5308-5310.
JP Pat. Application KOKAI publication No. 63-41470.
JP Pat. Application KOKAI publication No. 63-41471.
Tetrahedron Lett., 32(42), pp. 5987 to 5990, (1991).
Irvine, R., Biochemical Journal 204: 3-16 (1982).
Glaser, K.B., Advances in Pharmacology 32: 31-66 (1995).
Dennis, E. A., Trends in Biochemical Science, 22: 1-2 (1997).
Balsinde, J. et al, Annual Review of Pharmacology and Toxicology, 39: 175-189 (1999).
Uozumi, N. et al, Nature 390: 618-621 (1997).
Bonventre, J.V. et al, Nature 390: 622-625 (1997).
Nagase, Nature Immunology, 1:42-46 (2000).
Musser, J. Med. Chem., vol. 30, pp. 2087-2093 (1987).
J. Heterocycl. Chem., vol. 23, No. 3, pp. 701-704 (1986) [English Summary].
J. Org. Chem., vol. 55, No. 19, pp. 5308-5310 (1990).
Ishimitsu Keiichi
Nishibe Tadayuki
Takagi Masae
Lahive & Cockfield LLP
Laurentano Anthony A.
McKane Joseph K.
Nippon Soda Co. Ltd.
Shiao Robert
LandOfFree
Oxa(thia)zolidine compounds, process for preparation thereof... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Oxa(thia)zolidine compounds, process for preparation thereof..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Oxa(thia)zolidine compounds, process for preparation thereof... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-3777069