Oxa acids and related compounds for treating skin conditions

Details Oxa acids and related compounds for treating skin conditions Oxa acids and related compounds for treating skin conditions

1998-09-14

2000-06-06

Spivack, Phyllis G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Radical -xh acid, or anhydride, acid halide or salt thereof...

514513, 514559, 514560, A61K 3119, A61K 31255, A61K 31265

Patent

active

060719621

ABSTRACT:
Disclosed the use of compounds of Formula (I) depicted below, as active principals for treating skin conditions, compositions containing these compounds, and methods of treating skin conditions using these compounds and compositions. ##STR1## where R.sub.4 is (CR.sub.5 R.sub.6 --CR.sub.7 R.sub.8 --X.sub.1).sub.n --CR.sub.9 R.sub.10 R.sub.11 ; n is an integer from 1 to 18; R.sub.1, R.sub.2, R.sub.3, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10 and R.sub.11 are, independently, hydrogen or non-hydrogen substituents comprising alkyls, alkenyls, oxa-alkyls, aralkyls and aryls; and X, X.sub.1, Y and Z are, independently, oxygen, amine or sulfur, with preferred compounds being those in which X, X.sub.1, Y and Z are oxygen, and R.sub.1, R.sub.2, R.sub.3, R.sub.5, R.sub.6, R.sub.7, R.sub.8, R.sub.9, R.sub.10 and R.sub.11 are hydrogen.

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