Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Blood proteins or globulins – e.g. – proteoglycans – platelet...
Reexamination Certificate
2004-05-10
2009-11-17
Blanchard, David J. (Department: 1643)
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Blood proteins or globulins, e.g., proteoglycans, platelet...
C530S388100, C530S388850, C530S391100, C424S130100, C424S138100, C424S141100, C424S155100, C424S178100, C435S007100, C435S007200, C435S007230
Reexamination Certificate
active
07619068
ABSTRACT:
The invention provides isolated anti-ovarian, pancreatic, lung or breast cancer antigen (Ovr110) antibodies that internalize upon binding to Ovr110 on a mammalian in vivo. The invention also encompasses compositions comprising an anti-Ovr110 antibody and a carrier. These compositions can be provided in an article of manufacture or a kit. Another aspect of the invention is an isolated nucleic acid encoding an anti-Ovr110 antibody, as well as an expression vector comprising the isolated nucleic acid. Also provided are cells that produce the anti-Ovr110 antibodies. The invention encompasses a method of producing the anti-Ovr110 antibodies. Other aspects of the invention are a method of killing an Ovr110-expressing cancer cell, comprising contacting the cancer cell with an anti-Ovr110 antibody and a method of alleviating or treating an Ovr110-expressing cancer in a mammal, comprising administering a therapeutically effective amount of the anti-Ovr110 antibody to the mammal.
REFERENCES:
patent: 2002/0004587 (2002-01-01), Miller et al.
patent: 2003/0087250 (2003-05-01), Monahan et al.
patent: WO 99/63088 (1999-12-01), None
patent: WO 00/12758 (2000-03-01), None
patent: WO/00/12758 (2000-03-01), None
patent: WO 00/36107 (2000-06-01), None
patent: WO 02/06317 (2002-01-01), None
Yang, Green, Pinz-Sweeney, Briones, Burton, and Barbas. CDR walking mutagenesis for the affinity maturation of a potent human anti-HIV-1 antibody into the picomolar range. Journal of Molecular Biology, 1995. vol. 254, pp. 392-403.
Corral Laura
Keller Gilbert-Andre
Li Wenlu
Papkoff Jackie
Pilkington Glenn
Blanchard David J.
diaDexus, Inc.
Gussow Anne M.
Licata & Tyrrel P.C.
McCollum Keith R.
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