Ovo immunization against infectious bronchitis

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Virus or component thereof

Reexamination Certificate

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C424S204100, C424S093100, C424S093200

Reexamination Certificate

active

10858277

ABSTRACT:
The present invention is directed to processes and compositions for protecting host animals (e.g., chickens) from exposure to virulent infectious bronchitis virus. In ovo administration of live, avirulent strains of IB at appropriate dosage levels on a per egg basis provides an effective and efficient vaccination having acceptable safety and efficacy features.

REFERENCES:
patent: 5750113 (1998-05-01), Cook
patent: WO 99/53950 (1999-10-01), None
Chew et al., Avian Disease 41:598-603, 1997, Pathogenicity of Attenuated Infectious Bronchitis Virus for Oviducts of Chickens Exposed in Ovo.
Wakenell, et al., Am J Vet Res, vol. 47, No. 4, Apr. 1986, Chicken embryonal vaccination with avian infectious bronchitis virus.
Wakenell, et al., Avian Diseases 39:752-765, 1995, Embryo Vaccination of Chickens with Infectious Bronchitis Virus: Histologic and Ultrastructural Lesion Response and Immunologic Response to Vaccination.

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