Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Recombinant dna technique included in method of making a...
Reexamination Certificate
2007-04-03
2007-04-03
Guzo, David (Department: 1636)
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Recombinant dna technique included in method of making a...
C435S455000, C435S320100
Reexamination Certificate
active
10612713
ABSTRACT:
Methods for producing modified polypeptides containing amino acid analogues are disclosed, as well as compositions comprising purified dihydrofolate reductase polypeptides, produced by the methods of the invention. In certain aspects, methionine residues of the compositions are replaced with homoallyglycine, homoproparglycine, norvaline, norleucine, cis-crotyiglycine, trans-crotylglycine, 2-aminoheptanoic acid, 2-butynyiglycine and allyglycine.
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Kiick Kristi Lynn
Tirrell David A.
California Institute of Technology
Guzo David
Seed IP Law Group PLLC
LandOfFree
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