Ova fertilization assay

Details Ova fertilization assay Ova fertilization assay

1985-01-24

1988-09-20

Rosen, Sam

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving hydrolase

435 4, 435 24, 436 63, 436 65, C12Q 138, G01N 3348

Patent

active

047725540

ABSTRACT:
A method for assaying the fertilization potential of a mammalian ovum that has been removed from an ovarian follicle, together with a portion of accompanying follicular fluid. The method includes the step of measuring the concentration of at least one selected glycosaminoglycan in the follicular fluid accompanying the ovum to be tested. That concentration is then compared with concentrations of the same glycosaminoglycan characteristic of the follicular fluid of atretic and non-atretic follicles.

REFERENCES:
Bellin et al-Endocrinology, vol. 114, (1984), pp. 428-433.
Grimek et al-Biochem. & Biophys. Research Communications, vol. 104, No. 4, (1982), 1401-1406.
Ax et al-Biol. of Reproduction, vol. 20, (1979), pp. 1123-1132.

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