Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – 15 to 23 amino acid residues in defined sequence
Patent
1992-12-22
1993-11-02
Nutter, Nathan M.
Chemistry: natural resins or derivatives; peptides or proteins;
Peptides of 3 to 100 amino acid residues
15 to 23 amino acid residues in defined sequence
530327, 530328, 530395, 530840, 435 691, 4351723, C07K 500, C07K 700, C07K 1500, A61K 3702
Patent
active
052584941
ABSTRACT:
Disclosed are 1) osteogenic devices comprising a matrix containing osteogenic protein and methods of inducing endochondral bone growth in mammals using the devices; 2) amino acid sequence data, amino acid composition, solubility properties, structural features, homologies and various other data characterizing osteogenic proteins, 3) methods of producing osteogenic proteins using recombinant DNA technology, and 4) osteogenically and chondrogenically active synthetic protein constructs.
REFERENCES:
patent: 4294753 (1981-10-01), Urist
patent: 4394370 (1983-07-01), Jefferies
patent: 4434094 (1984-02-01), Seyedin et al.
patent: 4455256 (1984-06-01), Urist
patent: 4563350 (1986-01-01), Nathan et al.
patent: 4563489 (1986-10-01), Urist
patent: 4774322 (1988-09-01), Seyedin et al.
patent: 4804744 (1989-02-01), Sen
patent: 4810691 (1989-03-01), Seyedin et al.
patent: 4843063 (1989-06-01), Seyedin et al.
patent: 4877864 (1989-10-01), Wang et al.
patent: 5013649 (1991-05-01), Wang et al.
patent: 5106626 (1992-04-01), Parsons et al.
patent: 5106748 (1992-04-01), Wozney et al.
patent: 5108922 (1992-04-01), Wang et al.
patent: 5116738 (1992-05-01), Wang et al.
patent: 5141905 (1992-08-01), Rosen et al.
patent: 5166058 (1992-11-01), Wang et al.
patent: 5187076 (1993-02-01), Wozney et al.
Canalis et al. (1980) Science 210:1021-1023.
Glowacki et al. (1981) Lancet 1:959-963.
Reddi (1981) Collage Rel. Res. 1:209-226.
Sampath et al. (1981) Proc. Natl. Acad. Sci. USA 78:7599-7603.
Farley et al. (1982) Biochem. 21:3508-3513.
Maugh (1982) Science 217:819.
Sampath et al. (1983) Proc. Natl. Acad. Sci. USA 80:6591-6595.
Seyedin et al. (1983) J. Cell Biol. 97:1950-1953.
Urist et al. (1983) Proc. Soc. Exp. Bio. Med. 173:194-199.
Simpson (1984) Trends Biochem. Sci. 9:527-530.
Urist et al. (1984) Clin. Orth. Rel. Res. 187:277-280.
Urist et al. (1984) Proc. Natl. Acad. Sci. USA 81:371-375.
Centrella (1985) Proc. Natl. Acad. Sci. USA 82:7335-7339.
Klausner (1985) Biotechnology 3:567-568.
Olson et al. (1985) Analyt. Biochem. 146:232-237.
Reddi (1985) Journal of Biomedical Materials Research 19:233-239.
Sampath and Reddi (1985) Extracellular Matrix: Structure and Function (A. H. Reddi, Ed.) Allen R. Liss, Publ., NY pp. 412-428.
Seyedin et al. (1985) Proc. Natl. Acad. Sci. USA 82:2267-2271.
Colowick et al. (1987) Methods in Enzymology 146:294-312.
Padgett et al. Nature 325:81-84 (1987).
Sampath et al. (1987) Proc. Natl. Acad. Sci. USA 84:7109-7113.
Weeks et al. (1987) Cell 51:861-867.
LeGendre et al. (1988) Biotechniques 6:154-159.
Wang et al. (1988) Calcified Tissue Int. (Suppl) Ab No. 146, pp. A37.
Wang et al. II (1988) Proc. Natl. Acad. Sci. USA 85:9484-9488.
Wozney et al (1988) Calcified Tissue Int. (Suppl) Ab No. 146, pp. A37.
Wozney et al. II (1988) Science 242:1528-153.
Lyons et al. (1989) Proc. Natl. Acad. Sci. USA 86:4554-4558.
Wang et al. (1990) PNAS 87:2220-2224.
Kuberasampath Thangavel
Oppermann Hermann
Ozkaynak Engin
Rueger David C.
Nutter Nathan M.
Stryker Corporation
LandOfFree
Osteogenic proteins does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Osteogenic proteins, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Osteogenic proteins will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-1758692