Osteogenic composite matrix, method for the production...

Details Osteogenic composite matrix, method for the production... Osteogenic composite matrix, method for the production...

2009-10-02

2011-10-25

Kam, Chih-Min (Department: 1656)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S484000, C435S402000, C427S002260, C530S356000

Reexamination Certificate

active

08043627

ABSTRACT:
The invention relates to an osteogenic composite matrix consisting of collagen and non-collagen components of an extracellular matrix (ECM-components), to a method for producing said matrix, to a method for producing an implant or a scaffold for tissue engineering which is provided with a coating formed by said osteogenic composite matrix and is used for stimulating and accelerating a hard tissue formation such as, for example. The implant osseointegration in bones. The inventive osteogenic composite matrix comprises a collagen and at least one non-collagen ECM component or the derivatives thereof, wherein the collagen component consists of non-crosslinked collagen fibers produced by fibrillogenesis and the non-collagen ECM component or the derivatives thereof are integrated into said collagen fibers.

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