Surgery – Controlled release therapeutic device or system – Osmotic or diffusion pumped device or system
Patent
1988-12-28
1990-11-13
Yasko, John D.
Surgery
Controlled release therapeutic device or system
Osmotic or diffusion pumped device or system
604141, 604218, A61K 922, A61M 3700, A61M 5315
Patent
active
049698842
ABSTRACT:
An improved osmotic engine is disclosed. The osmotic engine is adapted to be used with an osmotically driven syringe which can be used to deliver a beneficial agent, such as a drug, at a pre-determined rate over an extended period of time. The osmotic engine has an exterior wall defining a compartment which contains an osmotic solute. The wall comprises a thin permeable and/or microporous material which is permeable to an external fluid such as water but is impermeable to the solute. The wall also has a delivery orifice drilled therethrough. A rigid non-dissolving ring-shaped wall support is provided for maintaining the shape of the engine during use. The wall support also provides a fluid flow path extending from the semipermeable wall portion toward the delivery orifice.
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ALZA Corporation
Mandell Edward L.
Miller D. Byron
Rose Sharon
Stone Steven F.
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