Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Patent
1997-10-22
2000-08-29
Page, Thurman K.
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
424476, 424479, 424480, 424482, 514356, 514960, A61K 924, A61K 920, A61K 932, A61K 914
Patent
active
061104981
ABSTRACT:
An osmotic drug delivery system, preferably in tablet form, which dispenses a therapeutic agent having limited water solubility in solubilized form. The delivery system comprises a core that is free of swellable polymers and comprises nonswelling solubilizing agents and wicking agents. The solubilized therapeutic agent is delivered through a passageway in the semipermeable coating of the tablet.
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Santus, G. and R.W. Baker, Journal of Controlled Release 35:1-21 (1989).
Burnside Beth A.
Couch Richard A.
Flanner Henry H.
Pinkett Jill E.
Rudnic Edward M.
Lillie Raymond J.
Olstein Elliot M.
Page Thurman K.
Seidleck Brian K.
Shire Laboratories Inc.
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