Surgery – Respiratory method or device – Ozone or ion generation
Patent
1975-11-24
1978-03-07
Pellegrino, Stephen C.
Surgery
Respiratory method or device
Ozone or ion generation
106196, 128213, 210500M, 264 49, 424 19, 424 20, A61M 3100
Patent
active
040774074
ABSTRACT:
An osmotic device for delivering an active agent is disclosed. The device is comprised of a wall surrounding a compartment and has a passageway through the wall for releasing the agent. The wall is formed of a multiplicity of materials comprising a material permeable to an external fluid and substantially impermeable to agent and at least one additional material selected from a material that imparts stability to the wall, enhances the permeability of the wall to fluids, or aids in forming the wall. The compartment comprises an active agent that exhibits an osmotic pressure gradient against an external fluid, or the agent is mixed with an osmotically effective compound that exhibits an osmotic pressure gradient against the fluid. Agent is released from the device by fluid being imbibed through the wall into the compartment at a rate controlled by the permeability of the wall and the osmotic pressure gradient across the wall, to produce a solution containing agent that is released through the passageway at a controlled and continuous rate over a prolonged period of time.
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Ayer Atul D.
Theeuwes Felix
ALZA Corporation
Ciotti Thomas E.
Gron Teddy S.
Mandell Edward L.
Pellegrino Stephen C.
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