Surgery – Respiratory method or device – Ozone or ion generation
Patent
1975-09-08
1976-08-31
Medbery, Aldrich F.
Surgery
Respiratory method or device
Ozone or ion generation
128130, 128272, 128271, 128270, 222389, A61M 3100
Patent
active
039774040
ABSTRACT:
An osmotic device for delivering an active agent is disclosed. The device is comprised of a wall surrounding in at least a part, a reservoir containing agent. The wall is formed of a material permeable to an external fluid and impermeable to agent. The reservoir is formed of a microporous material permeable to agent and fluid, and having at least one micropore that is a passageway for release of agent. The agent is soluble in the fluid and exhibits an osmotic pressure gradient against the fluid, or the agent has limited solubility in the fluid and is admixed with an osmotically effective compound soluble in fluid that exhibits an osmotic pressure gradient against fluid. In operation, agent is released by fluid permeating through the wall into the reservoir producing a solution of agent or a solution of compound containing agent, which solution in either instance is released through the micropore to the exterior of the device.
REFERENCES:
patent: 3765414 (1973-10-01), Arlen
patent: 3845770 (1974-11-01), Theeuwes
patent: 3851648 (1974-12-01), Brooke
patent: 3878977 (1975-04-01), Carlisle
ALZA Corporation
Ciotti Thomas E.
Mandell Edward L.
Medbery Aldrich F.
Sabatine Paul L.
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