Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Tablets – lozenges – or pills
Reexamination Certificate
2006-03-07
2006-03-07
Page, Thurman K. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Tablets, lozenges, or pills
C424S468000, C424S472000, C424S482000
Reexamination Certificate
active
07008641
ABSTRACT:
The present invention provides an osmotic device containing controlled release venlafaxine in the core in combination with an anti-psychotic agent in a rapid release external coat. A wide range of anti-psychotic agents can be used in this device. Particular embodiments of the invention provide osmotic devices having predetermined release profiles. One embodiment of the osmotic device includes an external coat that has been spray-coated rather compression-coated onto the device. The device with spray-coated external core is smaller and easier to swallow than the similar device having a compression-coated external coat. The device is useful for the treatment of depression, anxiety or psychosis related disorders.
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Owen, J. R. and Nemeroff, C.B., New Antidepressants and the Cytochrome P450System: Focus on Venlafaxine, Nefaxodone, and Mirtazapine, Depression and Anxiety, 1198, vol. 7, Supp. 1, 24-32, 1998.
Faour Joaquina
Vergez Juan
Innovar L.L.C.
Matos Rick
Osmotica Corp.
Page Thurman K.
Sheikh Humera N.
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