Osmotic delivery system having space-efficient piston

Surgery – Controlled release therapeutic device or system – Osmotic or diffusion pumped device or system

Reexamination Certificate

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C424S422000

Reexamination Certificate

active

11353842

ABSTRACT:
An osmotic delivery system having a space-efficient piston is provided. The enclosure has an interior holding the piston, a protein or peptide, and an osmotic agent. The piston is movable with respect to an interior surface of the capsule, and defines a movable seal with the interior surface of the capsule. The movable seal separates the osmopolymer from the protein or peptide. The piston has a recess that receives at least a portion of the osmotic agent. The osmotic agent imbibes liquid from a surrounding environment to cause the piston to move and, in turn, cause delivery of the beneficial agent from the capsule.

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U.S. Appl. No. 08/595,761, entitled “Sustained Delivery of an Active Agent Using an Implantable System,” 23 pages.

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