Osmotic delivery system having space efficient piston

Details Osmotic delivery system having space efficient piston Osmotic delivery system having space efficient piston

2005-03-29

2005-03-29

Kennedy, Sharon (Department: 3762)

Surgery

Controlled release therapeutic device or system

Osmotic or diffusion pumped device or system

C424S422000

Reexamination Certificate

active

06872201

ABSTRACT:
An osmotic delivery system having a space-efficient piston is provided. The enclosure has an interior holding the position, a beneficial agent, and an osmotic agent including a tablet. The piston is movable with respect to an interior surface of the capsule, and defines a movable seal with the interior surface of the capsule. The movable seal separates the osmotic agent from the beneficial agent. The piston has a recess that receives at least a portion of the osmotic agent. The osmotic agent imbibes liquid from a surrounding environment through a semipermeable body to cause the piston to move and in turn cause delivery of the beneficial agent from the capsule.

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U.S. patent application No. 08/595,761.
F. Theeuwes et al., “Principles of the Design and Operation of Generic Osmotic Pumps for the Delivery of Semisolid or Liquid Drug Formulation”, Annals of Biomedical Engineering 4 (1970), pp 343-353.

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