Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or...
Patent
1993-12-30
1996-12-31
Wityshyn, Michael G.
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
435 14, 435 25, 435817, C12Q 100, C12Q 137, C12Q 126
Patent
active
055893260
ABSTRACT:
A new group of Os(II) and Os(III) compounds useful as redox mediators in electrochemical biosensors. These compounds have 1) low oxidation potential, 2) fast reaction kinetics between the electroactive center of an enzyme and the compound, 3) slow oxidation of osmium by oxygen, and 4) excellent solubility in aqueous medium. These mediators are particularly useful as a component of a reagent used in an electrochemical biosensor, wherein the biosensor is useful for measuring analytes from a biological fluid, such as blood.
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Deng Zhi D.
Jernigan Walter W.
McEnroe Robert J.
Muddiman Rebecca W.
Sigler Gerald F.
Amick Marilyn L.
Boehringer Mannheim Corporation
Kenemore Max J.
Leary Louise N.
Wityshyn Michael G.
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