Chemistry: molecular biology and microbiology – Measuring or testing process involving enzymes or... – Involving antigen-antibody binding – specific binding protein...
Reexamination Certificate
2006-05-09
2006-05-09
Caputa, Anthony C. (Department: 1646)
Chemistry: molecular biology and microbiology
Measuring or testing process involving enzymes or...
Involving antigen-antibody binding, specific binding protein...
C435S007100, C435S007200
Reexamination Certificate
active
07041463
ABSTRACT:
Methods for identifying modulators of receptor activity using orthologues of human receptors are described. Additionally, a method for identifying an animal model useful in the screening of potential therapeutic agents is provided. The genes for bradykinin B1receptors from five mammalian species, vervet monkey, rhesus macaque, tree shrew, dog and pig, as well as the genes for CXCR2 receptors from chimpanzee, gorilla, orangutan, rhesus, vervet and baboon have been cloned and characterized and are described herein.
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Auld Douglas S.
Baldwin John J.
Chen Xiao Ge
Horlick Robert
Strohl Barbara
Caputa Anthony C.
Dias Kathy Smith
Heslin Rothenberg Farley & & Mesiti P.C.
Kolker Daniel E.
Pharmacopeia Drug Discovery Inc.
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