Ortho-substituted benzoic acid derivatives for the treatment...

Details Ortho-substituted benzoic acid derivatives for the treatment... Ortho-substituted benzoic acid derivatives for the treatment...

2008-04-08

2008-04-08

Witherspoon, Sikarl A. (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acids and salts thereof

C562S450000, C514S562000, C514S563000

Reexamination Certificate

active

10518007

ABSTRACT:
The present invention provides a compound of formula (I), wherein n is 0, 1 or 2 and R1represents halo, a C1-4alkyl group which is optionally substituted by one or more fluoro, a C1-4alkoxy group which is optionally substituted by one or more fluoro and wherein when n is 2 the substituents R1may be the same or different; R2represents a C2-8alkyl group which is optionally interrupted by oxygen; Y is absent or represents methylene; and X is O or S; and pharmaceutically acceptable salts and prodrugs thereof, to processes for preparing such compounds, to their utility in treating clinical conditions associated with insulin resistance, to methods for their therapeutic use and to pharmaceutical compositions containing them

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