Ortho-subsituted benzoylguanidines, process for their preparatio

Details Ortho-subsituted benzoylguanidines, process for their preparatio Ortho-subsituted benzoylguanidines, process for their preparatio

1997-02-21

1999-01-05

Henley, III, Raymond

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

514617, C07C23300

Patent

active

058565744

ABSTRACT:
Ortho-substituted benzoylguanidines, process for their preparation, their use as a medicament or diagnostic, and medicament containing them
Ortho-substituted benzoylguanidines of the formula I ##STR1## in which R(2) and R(3) have the meanings given in the claims, are suitable, as antiarrhythmic pharmaceuticals having a cardioprotective component, for the prophylaxis and treatment of infarction and for the treatment of angina pectoris. They also inhibit, in a preventive manner, the pathophysiological processes associated with the development of ischemically induced damage, in particular in association with the triggering of ischemically induced cardiac arrhythmias.

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