Ortho- and para-imidazolyl and benzimidazolyl substituted phenol

Details Ortho- and para-imidazolyl and benzimidazolyl substituted phenol Ortho- and para-imidazolyl and benzimidazolyl substituted phenol

1988-05-31

1991-08-27

Kepplinger, Esther L.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving antigen-antibody binding, specific binding protein...

435 28, 435810, 435968, 435975, 252700, C12Q 100, C12Q 128, C09K 300

Patent

active

050432664

ABSTRACT:
Light obtained from the reaction between a dihydrophthalazinedione such as luminol or isoluminol, an oxidant such as hydrogen peroxide, and a peroxidase enzyme is enhanced by addition of an ortho- or para- imidazolyl- or benzimidazolylphenol.
The effect has particular application to diagnostic assays.

REFERENCES:
patent: 4729950 (1988-03-01), Kricka et al.
patent: 4853327 (1989-08-01), Dattagupta
Thorpe, G. H. et al., Clin. Chem., 31(8):1335-1341, 1985.
I. Fridovich et al., J. Biol. Chem. 238, 3921-3927 (1963).
W. Straus, J. Histochem. Cytochem. 30, 491-493 (1982).
T. P. Whitehead et al., Clinical Chemistry 25, 1531-1546 (1979).

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