Ortho-alkylation of aromatic amines

Details Ortho-alkylation of aromatic amines Ortho-alkylation of aromatic amines

1990-09-13

1991-12-10

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

502231, C07C 4500

Patent

active

050720473

ABSTRACT:
A catalytic intermediate useful in the preparation of ortho-alkylated aromatic amines is prepared by heating an amine in the presence of aluminum metal, zinc metal and aluminum chloride. This catalytic intermediate is used to alkylate aromatic amines which may be the same as or different from the amine used in the catalytic intermediate preparation. In a preferred embodiment, toluenediamine is alkylated in the ortho positions to form diethyltoluenediamine.

REFERENCES:
patent: 2014766 (1935-09-01), Isham
patent: 2762845 (1956-09-01), Stroh et al.
patent: 2814646 (1957-11-01), Kolka et al.
patent: 3275690 (1966-09-01), Stroh et al.
patent: 3649693 (1972-03-01), Napolitano
patent: 3654331 (1972-04-01), Klopfer
patent: 3923892 (1975-12-01), Klopfer
patent: 4128582 (1978-12-01), Governale et al.
patent: 4219502 (1980-08-01), Ihrman et al.
patent: 4754066 (1988-06-01), Buysch et al.
patent: 4760185 (1988-07-01), Becker
patent: 4973759 (1990-11-01), Klein et al.
Parshall et al., "Homogeneous Catalysis for Agrochemicals, Flavors and Fragrances," Chemtech, Jun. 1988, pp. 376-383.
Stroh et al., "Alkylation of Aromatic Amines," Angew. Chem. 69, Jahrg. 1957, No. 4, pp. 124-131. (copy of international edition in English attached).
Grant et al., Grant & Hackh's Chemical Dictionary, Fifth Edition, p. 118, 1987.

Affiliated with

Also associated with

Rating

Ortho-alkylation of aromatic amines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Ortho-alkylation of aromatic amines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Ortho-alkylation of aromatic amines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1042260