Organometallic complexes of estrogens and their application to t

Details Organometallic complexes of estrogens and their application to t Organometallic complexes of estrogens and their application to t

1983-09-20

1987-04-07

Schenkman, Leonard

Chemistry: analytical and immunological testing

Biospecific ligand binding assay

436817, 514169, G01N 33566, A61K 3156

Patent

active

046561420

ABSTRACT:
The present invention relates to an estrogen complex which consists of an estrogen or an estrogen derivative complexed with an organometallic compound containing at least one free carbonyl ligand, the said estrogen complex containing at least one free hydroxyl radical and no free phenolic hydroxyl radical in the .alpha.-position to the site where the organometallic compound is attached.
The complexes according to the invention are useful for the determination of hormone receptors.

REFERENCES:
patent: 4205952 (1980-06-01), Cais
patent: 4466952 (1984-08-01), Hadd
Chem. Abstracts, vol. 101, No. 23 (1984), Par. 211551x.

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