Organometallic complexes of estrogens and their application to t

Details Organometallic complexes of estrogens and their application to t Organometallic complexes of estrogens and their application to t

1988-07-24

1991-01-08

Schenkman, Leonard

Organic compounds -- part of the class 532-570 series

Organic compounds

Cyclopentanohydrophenanthrene ring system containing

552625, C07J 900

Patent

active

049836463

ABSTRACT:
The present invention relates to an estrogen complex which consists of an estrogen or an estrogen derivative complexed with an organometallic compound containing at least one free carbonyl ligand, the said estrogen complex containing at least one free hydroxyl radical and no free phenolic hydroxyl radical in the .alpha.-position to the site where the organometallic compound is attached.
The complexes according to the invention are useful for the determination of hormone receptors.

REFERENCES:
patent: 4205952 (1980-06-01), Cais
The Merck Index, 10th Ed. (1983); #3648, Estradiol; #3649 .alpha.-Estradiol.
Biochemistry, 1988; vol. 27; pp. 6659-6666; Vessieres et al.

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