Organogermanium compounds

Details Organogermanium compounds Organogermanium compounds

1980-09-19

1982-11-30

Sneed, Helen M. S.

Drug, bio-affecting and body treating compositions

Nonspecific immunoeffector, per se ; or nonspecific...

Bacterium or component thereof or substance produced by said...

2604297, 544 64, 546 2, C07F 730, A01N 900, A61K 3128, A61L 1300

Patent

active

043615791

ABSTRACT:
A polycondensation product of a germanium trihydroxide compound of the formula: ##STR1## wherein W is hydrogen, alkyl, halogen, alkoxycarbonyl, carboxy, aryl, cycloalkyl which may be substituted, cycloalkenyl, heteroaryl or a group of the formula: (R.sup.1)(R.sup.2)N-- wherein R.sup.1 and R.sup.2 are each lower alkyl or R.sup.1 and R.sup.2 together with the adjacent nitrogen atom form a group of the formula: ##STR2## wherein R.sup.3 is hydrogen, lower alkyl, phenyl which may be substituted, aralkyl, acyl, acylamino or heteroaryl, and X is --N.dbd., --CH.dbd. or ##STR3## A is a bond, alkylene, alkenylene, --CO--Y--, --CONH--Y--, --O--Y--, --S--Y-- or ##STR4## (Y is alkylene); and R is alkyl. Such compounds are useful as agents for treating immune diseases.

REFERENCES:
patent: 3651018 (1972-03-01), Schade et al.
patent: 3689516 (1972-09-01), Asai et al.
patent: 3812167 (1974-05-01), Pahk
patent: 4066678 (1978-01-01), Sato et al.
patent: 4271084 (1981-06-01), Ishikawa et al.

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