Organic synthetic methods benzylpyrimidine derivatives

Details Organic synthetic methods benzylpyrimidine derivatives Organic synthetic methods benzylpyrimidine derivatives

1972-10-10

1978-09-26

Trousof, Natalie

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544323, C07D23748

Patent

active

041169581

ABSTRACT:
A method of preparation of 2,4-diamino-5-benzylpyrimidines involving the reaction of a 2,4-diamino-5-substituted methyl pyrimidine, for example 2,4-diamino-5-hydroxymethylpyrimidine, with an appropriately substituted phenol.

REFERENCES:
patent: 3819629 (1974-06-01), Roth et al.
Brit. J. Pharmacol. 6: 185-188 (1951), Falco et al.
JACS 73: 3758-3762 (1951), Falco et al.
J. Med. Pharm. Chem. 5:1103-1107, 1112, 1118 (1962) Roth et al.

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