Organic syntheses employing supercritical carbon dioxide as a re

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Synthesis of peptides

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530333, 530338, 564132, 564133, 564134, C07K 102, C07K 104

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active

052410480

ABSTRACT:
Chemical reactions are readily carried out using supercritical carbon dioxide as the reaction medium. Supercritical carbon dioxide is of special value as a reaction medium in reactions for synthesizing polypeptides, for sequencing polypeptides, or for amino acid analysis.

REFERENCES:
patent: 4483996 (1984-11-01), Jacobson
patent: 4820752 (1989-04-01), Berens
patent: 5001224 (1991-03-01), Barstow et al.
Kamihira, Chemical Abstracts, 109(9): 73891v, 1987.
Hyatt, John., J. Org. Chem., 49: 5097-5101, 1984.
Sigman, Michael, J. Org. Chem., 52: 1754-1757, 1987.

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