Organic polymer compound and production therof

Synthetic resins or natural rubbers -- part of the class 520 ser – Synthetic resins – Compositions to be polymerized by wave energy wherein said...

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522182, 522183, 424 7818, 424 7832, 424 7835, C08F 246

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active

058890785

ABSTRACT:
A homopolymer of acrylic acid or methacrylic acid derivatives having the general formula: ##STR1## wherein R.sup.1 represents a hydrogen atom or methyl group; R.sup.2 is a residue of a compound having physiological activity; X is a residue of a compound having a hydroxyl group, amino group or carboxyl group at both ends in its chemical structure after bonding between such compound and acrylic or methacrylic acid, and between such compound and the physiologically active compound; and the homopolymer has a number-average molecular weight ranging from 20,000 to 200,000; and a process for the preparation thereof by a mechanochemical polymerization reaction; as well as a polymeric drug and prodrug comprising the homopolymer.

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Merck Index, 9th Ed., 1976, p. 786.
Aldrich Catalog, 1990-1991, p. 890, 1081 Hawley's Condensed Chemical Dictionary, 11th Ed, Van Nostrand, New York 1987, p. 424.

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