Organic peptide containing substance recovered from blood having

Details Organic peptide containing substance recovered from blood having Organic peptide containing substance recovered from blood having

1977-11-03

1979-02-13

Rosen, Sam

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

424177, 424178, A61K 3514, A61K 3700, A61K 3726

Patent

active

041396111

ABSTRACT:
Organic peptide containing substances with insulin-like activity derived from blood or a blood component of a warm-blooded animal, which comprises the steps of pre-treating the blood or blood component by adjusting the pH thereof to a value of from 2 to 4 or of from 8 to 10, incubating the pre-treated blood at a temperature of from about 15 to about 40.degree. C for a period of at least four hours, cooling the incubated blood to a temperature of less than 10.degree. C, and recovering from the treated blood after neutralization organic peptide substances having a molecular weight of from about 1000 to about 5000, and an insulin-like activity of from about 14 to about 40 .mu.U/mg solid.

REFERENCES:
bromer et al., Chem. Abst., vol. 66 (1967), p. 62234a.

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