Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Ester doai
Patent
1993-09-07
1995-06-27
O'Sullivan, Peter
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Ester doai
514432, 514445, 549 28, 549 64, 558482, 558483, A61K 3121
Patent
active
054280613
ABSTRACT:
New organic nitrate compounds, formed by condensing a nitrato alkanoic acid with a sulfur-containing amino acid or peptide, which prevent nitrate tolerance or overcome existing tolerance and which are useful for the treatment of cardiac diseases including circulatory diseases, high blood pressure, cardiac insufficiency and for dilating the peripheral vessels.
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Campbell et al "Preparation and reaction of nitrate esters . . . " Chem Abst. 78(21):136650e (1973) & structure of RN 38660-08-01.
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Hutter Joachim
Noack Eike
Sandrock Klaus
Burn Brian M.
O'Sullivan Peter
Schwarz Pharma AG
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