Organic extract of Geum japonicum Thunb variant and use...

Details Organic extract of Geum japonicum Thunb variant and use... Organic extract of Geum japonicum Thunb variant and use...

2008-06-17

2008-06-17

Tate, Christopher R. (Department: 1655)

Drug, bio-affecting and body treating compositions

Plant material or plant extract of undetermined constitution...

Reexamination Certificate

active

07387801

ABSTRACT:
An organic extract of a Chinese herbal medicineGeum Japonicum thunbvar. has been identified that displayed potent stimulatory effects on rapid agiogenesis (<24 h), myogenesis and blocking fibrosis in traumatized skeletal muscles. The extract has displayed potent dual effects on angiogenesis and myogenesis in damaged skeletal muscles leading to complete skeletal muscle healing in rabbit and rat animal models. The extract of the present invention can be developed into an effective therapeutic drug for the treatment of skeletal muscle trauma, soft tissue healing including burn, skin wound and operation cut, and bone fracture and defect healings.

REFERENCES:
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patent: 7-179347 (1995-07-01), None
1998. Dong et al. Effects of Tannins fromGeum japoniumon the Catalytic Activity of Thrombin and factor Xa of Blood Coagulation Cascade. J. Natural products. 61. 1356-1360.
Kumar et al.: Fibrous Lesions of Bones.: RadioGraphics. 1990. 10; 237-256.

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