Organic copper complexes as radioprotectants

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heavy metal containing doai

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556115, 556116, 514500, C07F 108, A01N 5502, A61K 3130

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active

046579281

ABSTRACT:
Methods are described for using organic copper complexes or their solvates, which exhibit superoxide dismutase activity and act as superoxide radical scavengers, as radioprotectants to protect mammalian cells from damage caused by gamma- or x-irradiation. Treatment can result in the protection of normal tissues in cancer patients undergoing radiotherapy and in the protection of individuals who may be at risk with regard to hazardous effects of exposure to occupational or environmental ionizing radiation.

REFERENCES:
patent: 3884949 (1975-05-01), Eicke et al.
patent: 4221785 (1980-09-01), Sorenson
patent: 4287190 (1981-09-01), Boettcher et al.
patent: 4373953 (1983-02-01), Deinet et al.
Chemical Abstracts 69 113013z (1968).
Chemical Abstracts 84 38591r (1976).
Chemical Abstracts 85 116777t (1976).
Leuthauser, Antitumor Activities of Superoxide Dismutase and Copper Coordination Compounds, Ph.D. Thesis Iowa City, University of Iowa (1979).
Beauchamp et al, Anal. Biochem. 44 276-287 (1971).
Sorenson, J. Med. Chem. 19 135-148 (1976).
Georgieff, Science 173 537-539 (1971).
Sorenson, Inflammation 1 317-331 (1976).
Leuthauser et al, J. Nat'l Cancer Inst. 66 1077-1081 (1981).
Westman et al, Cancer Res. 41 2962-2966 (1981).
Oberley et al, Cancer Res. 39 1141-1149 (1979).

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